منابع مشابه
NMDA channels control meal size via central vagal afferent terminals.
The N-methyl-D-aspartate (NMDA) ion channel blocker MK-801 administered systemically or as a nanoliter injection into the nucleus of the solitary tract (NTS), increases meal size. Furthermore, we have observed that ablation of the NTS abolishes increased meal size following systemic injection of dizocilpine (MK-801) and that MK-801-induced increases in intake are attenuated in rats pretreated w...
متن کاملEstradiol: a rhythmic, inhibitory, indirect control of meal size.
The classic analyses of the inhibitory effects of cholecystokinin (CCK) on meal size, conducted by Professor Gerard P. Smith and his colleagues at the Bourne Laboratory, inspired my initial interest in this field. My current research, which investigates the role of estradiol in the control of meal size, continues to be guided by Gerry's thoughtful, scientific approach to the study of ingestive ...
متن کاملA closed-loop artificial pancreas using model predictive control and a sliding meal size estimator.
The objective of this article is to present a comprehensive strategy for a closed-loop artificial pancreas. A meal detection and meal size estimation algorithm is developed for situations in which the subject forgets to provide a meal insulin bolus. A pharmacodynamic model of insulin action is used to provide insulin-on-board constraints to explicitly include the future effect of past and curre...
متن کاملMeal-synchronized CEA in rats: effects of meal size, intragastric feeding, and subdiaphragmatic vagotomy.
Within a feeding schedule of intermittent food access, large meals have the ability to induce activity at the same time the next day [circadian ensuing activity (CEA)]. In these experiments, we evaluated the minimum meal size necessary to induce CEA and whether oral-pharyngeal factors and afferent vagal activity played necessary roles in the induction of the underlying process. In experiment 1,...
متن کاملMeal-Sensing Signaling Pathways in Functional Dyspepsia
Citation: Page AJ and Li H (2018) Meal-Sensing Signaling Pathways in Functional Dyspepsia. Front. Syst. Neurosci. 12:10. doi: 10.3389/fnsys.2018.00010 The upper gastrointestinal tract plays an important role in sensing the arrival, amount and chemical composition of a meal. Ingestion of a meal triggers a number of sensory signals in the gastrointestinal tract. These include the response to mech...
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ژورنال
عنوان ژورنال: Physiology & Behavior
سال: 2011
ISSN: 0031-9384
DOI: 10.1016/j.physbeh.2010.11.013